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SEOM Clinical Guideline of management of soft-tissue sarcoma (2020)

Fecha de publicación: Fecha Ahead of Print:

Autores de IDIVAL

  • Ana De Juan Ferré

    Autor

Autores ajenos al IDIVAL

  • Álvarez Álvarez R
  • Casado Herráez A
  • Cruz Jurado J
  • Estival González A
  • Martín-Broto J
  • Martínez Marín V
  • Moreno Vega A
  • Sebio García A
  • Valverde Morales C

Unidades

Abstract

Soft-tissue sarcomas constitute an uncommon and heterogeneous group of tumors of mesenchymal origin. Diagnosis, treatment, and management should be performed by an expert multidisciplinary team. MRI/CT of the primary tumor and biopsy is mandatory before any treatment. Wide surgical resection with tumor-free tissue margin is the mainstay for localized disease. Radiotherapy is indicated in large, deep, high-grade tumors, or after marginal resection not suitable for re-excision. Perioperative chemotherapy should be discussed for high-risk sarcomas of the extremities and trunk-wall. In the case of oligometastatic disease, patients should be considered for local therapies. First-line treatment with anthracyclines (or in combination with ifosfamide) is the treatment of choice. Other drugs have shown activity in second-line therapy and in specific histological subtypes but options are limited and thus, a clinical trial should always be discussed.

Datos de la publicación

ISSN/ISSNe:
1699-048X, 1699-3055

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico  SPRINGER

Tipo:
Practice Guideline
Páginas:
922-930
PubMed:
33405052

Citas Recibidas en Web of Science: 30

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Keywords

  • Guidelines; Sarcoma; Soft-tissue tumors; Uncommon tumors

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