Actividad Investigadora
Development and validation of quick Acute Kidney Injury-score (q-AKI) to predict acute kidney injury at admission to a multidisciplinary intensive care unit
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Autores de IDIVAL
Autores ajenos al IDIVAL
- Ferrari F
- Puci MV
- Ferraro OE
- Romero-González G
- Husain-Syed F
- Rizo-Topete L
- Senzolo M
- Lorenzin A
- Muraro E
- Baracca A
- Molano Triviño A
- Coutinho Castro A
- De Cal M
- Corradi V
- Brendolan A
- Scarpa M
- Carta MR
- Giavarina D
- Bonato R
- Iotti GA
- Ronco C
Unidades
Abstract
AKI is associated with increased risk of death, prolonged length of stay and development of de-novo chronic kidney disease. The aim of our study is the development and validation of prediction models to identify the risk of AKI in ICU patients up to 7 days. We retrospectively recruited 692 consecutive patients admitted to the ICU at San Bortolo Hospital (Vicenza, Italy) from 1 June 2016 to 31 March 2017: 455 patients were treated as the derivation group and 237 as the validation group. Candidate variables were selected based on a literature review and expert opinion. Admission eGFR<90 ml/min /1.73 mq (OR 2.78; 95% CI 1.78-4.35; p<0.001); SOFAcv >= 2 (OR 2.23; 95% CI 1.48-3.37; p<0.001); lactate >= 2 mmol/L (OR 1.81; 95% CI 1.19-2.74; p = 0.005) and (TIMP-2).(IGFBP7) >= 0.3 (OR 1.65; 95% CI 1.08-2.52; p = 0.019) were significantly associated with AKI. For the q-AKI score, we stratified patients into different AKI Risk score levels: 0-2; 3-4; 5-6; 7-8 and 9-10. In both cohorts, we observed that the proportion of AKI patients was higher in the higher score levels.
Datos de la publicación
- ISSN/ISSNe:
- 1932-6203, 1932-6203
- Tipo:
- Article
- Páginas:
- -
- PubMed:
- 31220087
PLOS ONE PUBLIC LIBRARY SCIENCE
Citas Recibidas en Web of Science: 11
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