Management of Psoriatic Arthritis in Patients With Comorbidities: An Updated Literature Review Informing the 2021 GRAPPA Treatment Recommendations

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Autores de IDIVAL

Autores ajenos al IDIVAL

  • Campanholo CB
  • Maharaj AB
  • Corp N
  • Bell S
  • Costa L
  • de Vlam K
  • Gullick NJ
  • Khraishi M
  • Kishimoto M
  • Reddy S
  • Scarpa R
  • Vega L
  • Duarte GV
  • Zisman D
  • van der Windt DA
  • Duruoz MT
  • Ogdie A

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Abstract

Objective. The 2021 Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) treatment recommendations provide an evidence-based guide for selecting therapy based on the individual's disease features. Beyond the disease features and associated conditions (eg, uveitis and inflammatory bowel disease), comorbidities play an important role in selecting therapy for an individual patient.Methods. We performed a systematic literature review. We examined the available evidence to inform treat-ment selection based on the presence or absence of comorbidities in psoriatic arthritis (PsA). Results. Common comorbidities in PsA that may affect treatment selection include presence of baseline car-diovascular disease (CVD) or high risk for CVD, obesity and metabolic syndrome, liver disease, mood dis-orders, including depression in particular, chronic infections, malignancies, osteoporosis, and fibromyalgia and/or central sensitization.Conclusion. Comorbidities may influence both the effectiveness of a given therapy but also the potential for adverse events. It is important to assess for the presence of comorbidities prior to therapy selection.

Copyright © 2023 by the Journal of Rheumatology.

Datos de la publicación

ISSN/ISSNe:
0315-162X, 1499-2752

JOURNAL OF RHEUMATOLOGY  J RHEUMATOL PUBL CO

Tipo:
Review
Páginas:
426-432
PubMed:
36319003

Citas Recibidas en Web of Science: 24

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Keywords

  • GRAPPA; comorbidities; psoriatic arthritis; treatments

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