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Quality of life improvement in patients with bone metastases undergoing palliative radiotherapy

Fecha de publicación: Fecha Ahead of Print:

Autores de IDIVAL

Autores ajenos al IDIVAL

  • Gomez-Iturriaga, Alfonso
  • Casquero, Francisco
  • Rades, Dirk
  • Navarro, Arturo
  • del Hoyo, Olga
  • Morillo, Virginia
  • Willisch, Patricia
  • Lopez-Guerra, JL
  • Illescas-Vacas, Ana
  • Ciervide, Raquel
  • Martinez-Indart, Lorea
  • Cacicedo, Jon

Unidades

Abstract

Background:The aim of the study was to analyze the impact of palliative radiotherapy on quality of life (QoL) in patients with symptomatic bone metastases. Materials and methods: We present the results from a prospective multicentric study including 128 patients who provided pre-and post-radiotherapy (one month after treatment) brief pain inventory (BPI) assessments. Worst pain was recorded using the BPI (range: 0-10). Pain response was described according to the International Bone Metastases Consensus on palliative radiation. Regarding QoL, for each pre-and post-radiation BPI-questionnaire, scores from the interference domains were summed and averaged to obtain an overall interference score. Results: There was a significant correlation between radiation treatment response and improvement in all functional interference domains except sleeping. Patients > 75 years old presented a significantly higher improvement in general activity, mood and relationships with others compared to patients <= 75 years old. Patients presenting a baseline pain score >= 8 showed a higher improvement in the general activity item (p = 0.049). There was no statistically significant association between pre-treatment ECOG, chemotherapy, primary tumor location and radiation schedule with any of the functional interference items. Conclusions: Patients who report pain relief after palliative radiotherapy also present a better quality of life including physical and psychosocial aspects.

© 2022 Greater Poland Cancer Centre.

Datos de la publicación

ISSN/ISSNe:
1507-1367, 2083-4640

REPORTS OF PRACTICAL ONCOLOGY AND RADIOTHERAPY  Elsevier Urban/Partner Sp. z.o.o.

Tipo:
Article
Páginas:
428-439
PubMed:
36186707

Citas Recibidas en Web of Science: 4

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Keywords

  • bone metastases; pain; palliative radiotherapy; quality of life

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