Actividad Investigadora
Caracterización de las bases moleculares de la vasculitis mediada por IgA
Datos básicos
Objetivos del proyecto
El objetivo principal del presente proyecto es la caracterización de las bases moleculares de la IgAV mediante: A- Identificación de patrones de expresión génica y perfiles de metilación específicos de la IgAV a través de la comparación de éstos en pacientes diagnosticados con dicha patología y controles sanos. B- Identificación de variantes genéticas asociadas a la IgAV que influyan en los niveles de expresión génica (eQTLs) y demetilación (MeQTLs) a través de un análisis integrador de diferentes datos "-ómicos" (genéticos, de expresión y epigenéticos).
Documentos
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Participantes
Unidades de investigación
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Resultados del Proyecto
?Idiopathic pulmonary fibrosis or interstitial lung disease associated to connective tissue diseases? Endothelial progenitor cells as a potential tool for the differential diagnosis
Pulito-Cueto, V; (...); Cifrian, JM
Meeting Abstract. 10.1183/13993003.congress-2020.2584. 2020
BAFF-APRIL-BAFFR PATHWAY ON THE PATHOGENESIS OF IMMUNOGLOBULIN-A VASCULITIS
Prieto-Pena, D; (...); Lopez-Mejias, R
Meeting Abstract. 10.1136/annrheumdis-2021-eular.707. 2021
CHARACTERIZING THE PRE-DISEASE STATE OF PSORIATIC ARTHRITIS: CXCL10 LEVELS ARE ASSOCIATED WITH SUBCLINICAL SYNOVITIS IN PATIENTS WITH PSORIASIS
Pulito-Cueto, V; (...); Rueda-Gotor, J
Meeting Abstract. 10.1136/annrheumdis-2023-eular.5466. 2023
Elevated VCAM-1, MCP-1 and ADMA serum levels related to pulmonary fibrosis of interstitial lung disease associated with rheumatoid arthritis
Pulito-Cueto, V; (...); Gonzalez-Gay, MA
Article. 10.3389/fmolb.2022.1056121. 2022
ENDOTHELIAL PROGENITOR CELLS: ROLE IN ENDOTHELIAL DAMAGE OF INTERSTITIAL LUNG DISEASE ASSOCIATED TO RHEUMATOID ARTHRITIS
Pulito-Cueto, V; (...); Gonzalez-Gay, MA
Meeting Abstract. 10.1136/annrheumdis-2020-eular.3228. 2020
ENDOTHELIN-1 AS A POTENTIAL CANDIDATE TO SHED LIGHT ON THE CHALLENGE OF INTERSTITIAL LUNG DISEASE DIAGNOSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS
Pulito-Cueto, V; (...); González-Gay, MA
Meeting Abstract. 10.1136/annrheumdis-2023-eular.2007. 2023
IGA VASCULITIS AND IGA NEPHROPATHY SHARE A SIMILAR IL17A ASSOCIATION PATTERN
Prieto-Pena, D; (...); Lopez-Mejias, R
Meeting Abstract. 10.1136/annrheumdis-2021-eular.766. 2021
IGAV AND IGAN: A SINGLE ENTITY REGARDING CD40, BLK AND BANK1 POLYMORPHISMS
Pulito-Cueto, V; (...); López-Mejías, R
Meeting Abstract. 2023
Influence of IL17A gene on the pathogenesis of immunoglobulin-A vasculitis
Lopez-Mejias, R; (...); Gonzalez-Gay, MA
Article. 2020
INFLUENCE OF IL17A GENE ON THE PATHOGENESIS OF IMMUNOGLOBULIN-A VASCULITIS
Genre, F; (...); Lopez-Mejias, R
Meeting Abstract. 10.1136/annrheumdis-2020-eular.641. 2020
MUCOSAL IMMUNE DEFENCE POLYMORPHISMS: RELEVANT PLAYERS IN IGA VASCULITIS?
Pulito-Cueto, V; (...); López-Mejías, R
Meeting Abstract. 10.1136/annrheumdis-2023-eular.73. 2023
Osteopontin and interleukin-6 as biomarkers of interstitial lung disease
Martinez, SR; (...); Cifrian, JM
Meeting Abstract. 10.1183/13993003.congress-2020.2717. 2020
PLEUROPARENCHYMAL FIBROELASTOSIS: A SPECIAL CLINICAL SITUATION IN PATIENTS WITH INTERSTITIAL LUNG DISEASE ASSOCIATED WITH CONNECTIVE TISSUE DISEASES. DESCRIPTIVE STUDY FROM A REFERRAL CENTRE
Atienza-Mateo, B; (...); González-Gay, MA
Meeting Abstract. 10.1136/annrheumdis-2023-eular.1387. 2023
Role of IRF5 in the pathogenesis of immunoglobulin-A vasculitis
Genre, F; (...); Lopez-Mejias, R
Article. 2020
ROLE OF IRF5 GENE ON THE PATHOGENESIS OF IMMUNOGLOBULIN-A VASCULITIS
Martinez, SR; (...); Lopez-Mejias, R
Meeting Abstract. 10.1136/annrheumdis-2020-eular.1023. 2020
THE FIRST METHYLOME PROFILING STUDY OF B-CELLS IN IGA VASCULITIS REVEALED POTENTIAL BIOMARKERS OF DISEASE SUSCEPTIBILITY
Meeting Abstract. 10.1136/annrheumdis-2024-eular.117. 2025
THE INVOLVEMENT OF THE C5 AND C5AR1 GENES IN THE PATHOGENESIS OF IgAV
Meeting Abstract. 10.1136/annrheumdis-2024-eular.381. 2025
THE TRANSCRIPTOME PROFILE OF B CELLS: USEFUL NON-INVASIVE BIOMARKER FOR THE DIAGNOSIS OF NEPHRITIS IN IGA VASCULITIS
Meeting Abstract. 10.1136/annrheumdis-2025-eular.A174. 2025
