Actividad Investigadora
Caracterización de las bases moleculares de la vasculitis mediada por IgA
Datos básicos
- Código:
- PI18/00042
- Dotación:
- 130.075,00 €
- Año Inicial:
- 2019
- Año final:
- 2023
Objetivos del proyecto
El objetivo principal del presente proyecto es la caracterización de las bases moleculares de la IgAV mediante: A- Identificación de patrones de expresión génica y perfiles de metilación específicos de la IgAV a través de la comparación de éstos en pacientes diagnosticados con dicha patología y controles sanos. B- Identificación de variantes genéticas asociadas a la IgAV que influyan en los niveles de expresión génica (eQTLs) y demetilación (MeQTLs) a través de un análisis integrador de diferentes datos "-ómicos" (genéticos, de expresión y epigenéticos).
Unidades de investigación
Documentos
- No hay documentos
Participantes
Financiadores
Resultados del Proyecto
?Idiopathic pulmonary fibrosis or interstitial lung disease associated to connective tissue diseases? Endothelial progenitor cells as a potential tool for the differential diagnosis
Pulito-Cueto, V; (...); Cifrian, JM
Meeting Abstract. 10.1183/13993003.congress-2020.2584. 2020
BAFF-APRIL-BAFFR PATHWAY ON THE PATHOGENESIS OF IMMUNOGLOBULIN-A VASCULITIS
Prieto-Pena, D; (...); Lopez-Mejias, R
Meeting Abstract. 10.1136/annrheumdis-2021-eular.707. 2021
CHARACTERIZING THE PRE-DISEASE STATE OF PSORIATIC ARTHRITIS: CXCL10 LEVELS ARE ASSOCIATED WITH SUBCLINICAL SYNOVITIS IN PATIENTS WITH PSORIASIS
Pulito-Cueto, V; (...); Rueda-Gotor, J
Meeting Abstract. 10.1136/annrheumdis-2023-eular.5466. 2023
Elevated VCAM-1, MCP-1 and ADMA serum levels related to pulmonary fibrosis of interstitial lung disease associated with rheumatoid arthritis
Pulito-Cueto, V; (...); Gonzalez-Gay, MA
Article. 10.3389/fmolb.2022.1056121. 2022
ENDOTHELIAL PROGENITOR CELLS: ROLE IN ENDOTHELIAL DAMAGE OF INTERSTITIAL LUNG DISEASE ASSOCIATED TO RHEUMATOID ARTHRITIS
Pulito-Cueto, V; (...); Gonzalez-Gay, MA
Meeting Abstract. 10.1136/annrheumdis-2020-eular.3228. 2020
ENDOTHELIN-1 AS A POTENTIAL CANDIDATE TO SHED LIGHT ON THE CHALLENGE OF INTERSTITIAL LUNG DISEASE DIAGNOSIS IN PATIENTS WITH RHEUMATOID ARTHRITIS
Pulito-Cueto, V; (...); González-Gay, MA
Meeting Abstract. 10.1136/annrheumdis-2023-eular.2007. 2023
IGA VASCULITIS AND IGA NEPHROPATHY SHARE A SIMILAR IL17A ASSOCIATION PATTERN
Prieto-Pena, D; (...); Lopez-Mejias, R
Meeting Abstract. 10.1136/annrheumdis-2021-eular.766. 2021
IGAV AND IGAN: A SINGLE ENTITY REGARDING CD40, BLK AND BANK1 POLYMORPHISMS
Pulito-Cueto, V; (...); López-Mejías, R
Meeting Abstract. 2023
Influence of <i>IL17A</i> gene on the pathogenesis of immunoglobulin-A vasculitis
Lopez-Mejias, R; (...); Gonzalez-Gay, MA
Article. 2020
INFLUENCE OF IL17A GENE ON THE PATHOGENESIS OF IMMUNOGLOBULIN-A VASCULITIS
Genre, F; (...); Lopez-Mejias, R
Meeting Abstract. 10.1136/annrheumdis-2020-eular.641. 2020
MUCOSAL IMMUNE DEFENCE POLYMORPHISMS: RELEVANT PLAYERS IN IGA VASCULITIS?
Pulito-Cueto, V; (...); López-Mejías, R
Meeting Abstract. 10.1136/annrheumdis-2023-eular.73. 2023
Osteopontin and interleukin-6 as biomarkers of interstitial lung disease
Martinez, SR; (...); Cifrian, JM
Meeting Abstract. 10.1183/13993003.congress-2020.2717. 2020
PLEUROPARENCHYMAL FIBROELASTOSIS: A SPECIAL CLINICAL SITUATION IN PATIENTS WITH INTERSTITIAL LUNG DISEASE ASSOCIATED WITH CONNECTIVE TISSUE DISEASES. DESCRIPTIVE STUDY FROM A REFERRAL CENTRE
Atienza-Mateo, B; (...); González-Gay, MA
Meeting Abstract. 10.1136/annrheumdis-2023-eular.1387. 2023
Role of <i>IRF5</i> in the pathogenesis of immunoglobulin-A vasculitis
Genre, F; (...); Lopez-Mejias, R
Article. 2020
ROLE OF IRF5 GENE ON THE PATHOGENESIS OF IMMUNOGLOBULIN-A VASCULITIS
Martinez, SR; (...); Lopez-Mejias, R
Meeting Abstract. 10.1136/annrheumdis-2020-eular.1023. 2020